| 摘要 |
<p>A compound of the formula (I): <CHEM> wherein X is hydroxy or the like; Y is -C(=R<2>)-R<3>-R<4> wherein R<2> and R<3> is oxygen atom or the like, R<4> is hydrogen, optionally substituted alkyl, optionally substituted heteroaryl or the like; Z is hydrogen or the like; Z<1> and Z<3> each is independently a bond, alkylene or the like; Z<2> is a bond, alkylene, -O- or the like; R<1> is optionally substituted aryl, optionally substituted heteroaryl or the like; p is 0 to 2 and ring (A) is optionally substituted aromatic heterocycle, a tautomer of itself, a prodrug thereof, a pharmaceutically acceptable salt thereof or a solvate thereof has an integrase-inhibiting activity.</p> |
