发明名称 |
Process for the sterilization of biological compositions and the product produced thereby |
摘要 |
The present invention concerns a process for inactivating extracellular and intracellular virus in a biological composition without incurring substantial disruption or inactivation thereof, said process comprising subjecting said composition to a virucidally effective amount of UVA1 irradiation substantially in the absence of UVA2 irradiation for a period of time sufficient to thereby inactivate said virus while retaining functionality of said composition. The biological composition is advantageously a product that contains red blood cells or platelets. The process is advantageously carried out in the presence of an irradiation sensitizer compound and/or a quencher. The present invention also concerns the product substantially identical to that produced by the inventive process. |
申请公布号 |
US6413714(B1) |
申请公布日期 |
2002.07.02 |
申请号 |
US20000580250 |
申请日期 |
2000.05.26 |
申请人 |
NEW YORK BLOOD CENTER, INC. |
发明人 |
MARGOLIS-NUNNO HENRIETTA;BEN-HUR EHUD;HOROWITZ BERNARD |
分类号 |
A61K41/00;A61L2/00;C12N7/06;(IPC1-7):A01N1/02;A01N63/00;C12N13/00;C12N7/04 |
主分类号 |
A61K41/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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