发明名称 3,6-DISUBSTITUTED PENAM SULFONE DERIVATIVES AS ANTIBACTERIALS
摘要 <p>Compounds are provided having formulae (I) and (II) wherein n is 0 or 1 and when n=1, R is a 5 or 6 membered heterocyclic ring, hydroxy, halogen, oxo, carbamoyl, alkoxy, or disubstituted amino, when n=0, R is an ester, cyano or amide group; X is CH or NH; R3 is cyano, methoxy, or acetamido; R1 is hydrogen, alkyl, a negative charge, a cation selected from the group consisting of sodium, potassium and tetraalkylammonium and acyloxyalkyl, or alkoxycarbonyloxyalkyl; and R2 is hydrogen, acyl, trisubstituted silyl carbamoyl or an amino acid residue; or pharmaceutically acceptable salts thereof.</p>
申请公布号 SK10142001(A3) 申请公布日期 2002.07.02
申请号 SK20010001014 申请日期 2000.01.26
申请人 AMERICAN CYANAMID COMPANY 发明人 LIN YANG-I;BITHA PANAYOTA;LI ZHONG;FRANCISCO GERARDO DELACRUZ
分类号 A61K31/43;A61K31/431;A61P31/04;C07D499/00;C07D499/04;C07D499/86;C07D499/87;C07D499/897;(IPC1-7):C07D499/87 主分类号 A61K31/43
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