POLYMERIC COMPOSITION FOR SOLUBILIZING POORLY WATER SOLUBLE DRUGS AND PROCESS FOR THE PREPARATION THEREOF.

摘要

A composition capable of forming a micelle in body fluids or in an aqueous medium and that can be injected into the body undiluted or as a diluted solution in an aqueous medium and method for preparation thereof are disclosed. The composition comprises an amphiphilic block copolymer having a hydrophilic poly(alkylene glycol) component and hydrophobic biodegradable polymer component, contained in a poly(ethylene glycol) medium. Such composition is useful in the solubilization and administration of a poorly water soluble drug.