Novel uses of non-peptide bombesin receptor antagonists for treating anxiety andpanic disorders

摘要

New uses have been found for compounds of formula (I) in which Ar, Ar>1<, R>1<, R>2<, R>3<, R>4<, R>5<, R>6<, R>7<, R>8<, R>9<, j, k, l, m and n are as defined in the description. These uses for the diagnosis, prevention, or treatment of anxiety, social phobia and panic disorders, pulmonary hypertension, lung repair and lung development disorders, prostate cancer, pancreatic cancer, hepatic porphyria, visceral pain, gastrointestinal secretory disturbances including duodenal ulcer and Helicobacter pylori infection and neuropathic pain. There is also disclosed a method for diagnosing or treating cancers using a radiolabelled compound of Formula (I), and also a method for treating cancers using a conjugate of a compound of Formula (I) with a cytotoxic agent.