| 摘要 |
The derivatives of erythromycin and their salts can be used as antimicrobial agents. They have the general formula wherein R is H or lower alkyl; R1 is alkyl, cycloalkyl, (cycloalkyl)alkyl, aralkyl, or -(CH2)n-X-R4; R2 is H or acetyl; R3 is acyl or -C(=O)-Y-R5; R4 is alkyl, alkoxyalkyl, alkylthioalkyl, alkylaminoalkyl, aryl, or aralkyl; R5 is alkyl, aryl or aralkyl; n is an integer of 1 to 6; X is O, S or -NZ; Y is O or -NH-; and Z is H or alkyl. 8 claims
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