发明名称 |
Hepatitis-B-Oberflächenantigen enthaltendes Peptid |
摘要 |
An immunogenic particle comprises a plurality of first peptide monomers and a plurality of second peptide monomers, each of said first peptide monomers comprising : an amino acid sequence corresponding to a substantial portion of a peptide which upon secretion will form particles which are at least 10 nm in diameter, and an amino acid sequence corresponding to a heterologous epitope, each of said second peptide monomers comprising an amino acid sequence corresponding to a substantial portion of a peptide which upon secretion will form particles which are at least 10 nm in diameter, each of said second peptide monomers being free of an amino acid sequence corresponding to a heterologous epitope, wherein said first peptide monomer and said second peptide monomer are not identical but are capable of binding together. |
申请公布号 |
DE3856496(T2) |
申请公布日期 |
2002.06.27 |
申请号 |
DE19883856496T |
申请日期 |
1988.06.22 |
申请人 |
MEDEVA HOLDINGS B.V., AMSTERDAM |
发明人 |
THOMA, HANS A. DR. |
分类号 |
C12N15/09;A61K38/00;A61K39/00;A61K39/13;A61K39/135;A61K39/21;A61K39/29;A61K39/295;A61P31/12;C07K14/00;C07K14/005;C07K14/02;C07K14/10;C07K14/105;C07K14/155;C07K14/18;C07K14/195;C07K14/44;C07K14/445;C07K14/705;C07K19/00;C12N1/21;C12N5/10;C12N15/62;C12P21/00;C12P21/02;C12R1/19;C12R1/91;(IPC1-7):C12N15/00 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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