DESOXYRIBONUCLEIC ACIDS CODING FOR THE EQUINE IGE-ALLOTYPE HEAVY CHAIN CONSTANT REGION, THE RECOMBINANT IMMUNOGLOBULIN OBTAINED THEREWITH AND CORRESPONDING ISOTYPE-SPECIFIC MONOCLONAL ANTIBODIES AND THE UTILIZATION THEREOF

摘要

The invention relates to novel equine C epsilon and C epsilon genes coding for IgE-allotypes heavy chain constant regions and used in the production of IgE-isotype recombinant immunoglobulin. Said recombinant immunoglobulins represent valuable auxiliary agents for IgE-diagnosis, especially equine allergy diagnosis. With the aid of the recombinant IgEs, antibodies are obtained that can be used in allergy diagnosis, inter alia, in ELISA-based test kits.