| 发明名称 |
Methods for identifying inhibitors of helicase C virus |
| 摘要 |
Assay methods are disclosed having utility in the identification of therapeutic agents effective against human hepatitis C virus and related viruses. NS3 protein derived from these viruses, representing a native and authentic version of the complete protein sequence, is used in the assay methods of the invention, which enables identification and development of anti-viral agents exhibiting inhibition of the protein's NTPase and RNA helicase activities.
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| 申请公布号 |
US2002081574(A1) |
申请公布日期 |
2002.06.27 |
| 申请号 |
US20010010860 |
申请日期 |
2001.12.07 |
| 申请人 |
COLLETT MARC S.;PEVEAR DANIEL C.;GROARKE JAMES M.;YOUNG DOROTHY C. |
发明人 |
COLLETT MARC S.;PEVEAR DANIEL C.;GROARKE JAMES M.;YOUNG DOROTHY C. |
| 分类号 |
C12N15/09;A61K38/00;C07K14/18;C12N9/14;C12N9/50;C12N15/00;C12N15/40;C12Q1/68;C12Q1/70;C12R1/91;G01N33/15;(IPC1-7):C12Q1/70;C12N9/22;C12N15/86;C12P21/02 |
主分类号 |
C12N15/09 |
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