摘要 |
The present invention relates to 11,12 .gamma. lactone ketolides of formula (I) wherein R, R1~, R2~, R3~ are as defined herein and pharmaceutically acceptable salts and solvates thereof, to process for their preparation and their use in therapy or prophylaxis of systemic or topical bacterial infections in a human or animal body.
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申请人 |
GLAXO GROUP LIMITED;PLIVA D.D. |
发明人 |
SERI, CATIA;TARSI, LUCA;ANDREOTTI, DANIELE;TIBASCO, JESSICA;TERRENI, SILVIA;MERLO, GIANCARLO;MARCHIORO, CARLA;NICCOLAI, DANIELA;MINGARDI, ANNA;PAIO, ALFREDO;PIGA, ELISABETTA;LOCIURO, SERGIO;DAMIANI, FREDERICA;CARDULLO, FRANCESCA;BIONDI, STEFANO;POZZAN, ALFONSO;ARISTA, LUCA;CIRACO, MANUELA;ALIHODZIC, SULEJMAN |