| 发明名称 |
Modified muteins of erythropoietin derived from in vitro or in vivo expression system of microorganism |
| 摘要 |
The present invention discloses modified muteins of erythropoietin (EPO) with increased biological activity derived from in vitro or in vivo expression system of microorganism exhibited a prolonged circulating half-life compared to unmodified muteins of EPO produced from microorganisms, and novel methods of preparing the selectively modified muteins of EPO.
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| 申请公布号 |
US2002081734(A1) |
申请公布日期 |
2002.06.27 |
| 申请号 |
US20010783721 |
申请日期 |
2001.02.14 |
| 申请人 |
CHOI CHA YONG;KANG SANG HYEON;KANG TAEK JIN;WOO JI HYOUNG |
发明人 |
CHOI CHA YONG;KANG SANG HYEON;KANG TAEK JIN;WOO JI HYOUNG |
| 分类号 |
C12N15/09;A61K38/22;A61P7/06;A61P43/00;C07K14/505;C12P21/02;(IPC1-7):C12P21/02;C07K14/47 |
主分类号 |
C12N15/09 |
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