NOVEL SPLA2 INHIBITORS

摘要

A novel class of tetracyclic compounds is disclosed represented by the formula (I), or a pharmaceutically acceptable salt, solvate, or prodrug derivative thereof; wherein; A is independently C, or N; n is 1, 2 or 3; together with the use of such compounds for inhibiting sPLA2 mediated release of fatty acids for treatment of Inflammatory Diseases such as septic shock.