| 摘要 |
The invention provides a method of selectively fluorinating an organic compound at an unactivated saturated sp<3> hybridised carbon atom, the method comprising reacting the compound with a fluorinating agent containing an N-F bond. The carbon atom may be, for example, a tertiary carbon atom or a secondary carbon atom. The carbon atom may form part of a cyclic structure. The fluorinating agent may be any electrophilic fluorinating agent containing an N-F bond. Preferably, the fluorinating agent is an N-fluorinated diazoniabicycloalkane. |
