| 发明名称 |
Formulation, apparatus and method for stabilizing radiopharmaceuticals |
| 摘要 |
A formulation for stabilizing a radiopharmaceutical. The formulation includes a radiopharmaceutical (or a pharmaceutically acceptable salt thereof), a gas which has oxygen, a stabilizer, and a solvent. |
| 申请公布号 |
US9345792(B2) |
申请公布日期 |
2016.05.24 |
| 申请号 |
US201113813687 |
申请日期 |
2011.08.15 |
| 申请人 |
Siemens Medical Solutions USA, Inc. |
发明人 |
Kolb Hartmuth C.;Walsh Joseph C.;Mocharla Vani P.;Mu Fanrong;Gangadharmath Umesh B. |
| 分类号 |
A61K51/04;A61K51/12;A61K9/00;A61K47/12 |
主分类号 |
A61K51/04 |
| 代理机构 |
|
代理人 |
Kendall Peter |
| 主权项 |
1. A formulation for stabilizing a radiopharmaceutical, the formulation comprising:
a F-18 labelled radiopharmaceutical, or a pharmaceutically acceptable salt of a F-18 labelled radiopharmaceutical thereof; a gas comprising oxygen; wherein the oxygen is present in the gas in an amount of at least about 10 vol. % by total volume of gas; and where the gas is disposed in a headspace of a vial containing the F-18 labelled radiopharmaceutical or the pharmaceutically acceptable salt of the F-18 labelled radiopharmaceutical stabilizer, wherein the stabilizer is maleic acid; and an alcohol. |
| 地址 |
Malvern PA US |
