| 发明名称 |
GLIAL CELL LINE-DERIVED NEUROTROPHIC FACTOR RECEPTORS |
| 摘要 |
Receptors for Glial Cell Line-Derived Neurotrophic Factor (GDNF), their cellular expression, isolation, biochemical characterization, and sequences are disclosed. c-RET is disclosed as one receptor for GDNF; additional novel receptors are also disclosed. The preparation of monoclonal antibodies directed against GDNF is also disclosed. |
| 申请公布号 |
EP1007072(A4) |
申请公布日期 |
2002.06.26 |
| 申请号 |
EP19980920199 |
申请日期 |
1998.05.04 |
| 申请人 |
CEPHALON, INC. |
发明人 |
IBANEZ, CARLOS, F.;ARUMAE, URMAS;SARIOLA, HANNU;SUVANTO, PETRO;TRUPP, MILES;SAARMA, MART |
| 分类号 |
C12N15/09;A61K31/711;A61K38/00;A61K38/22;A61K48/00;A61P19/08;A61P19/10;A61P35/00;A61P43/00;C07K14/705;C07K14/71;C07K16/28;C12P21/08 |
主分类号 |
C12N15/09 |
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