发明名称 Difluoro-hexahydro-cyclopentaoxazinyls and difluoro-hexahydro-benzooxazinyls as bace1 inhibitors
摘要 The present invention provides difluoro-cyclopentaoxazinyls and difluorobenzooxazinyls of formula (I) having BACE1 inhibitory activity, their manufacture, pharmaceutical compositions containing them and their use as therapeutically active substances. The active compounds of the present invention are useful in the therapeutic and/or prophylactic treatment of e.g. Alzheimer’s disease.
申请公布号 NZ702253(A) 申请公布日期 2016.06.24
申请号 NZ20130702253 申请日期 2013.06.24
申请人 F. HOFFMANN-LA ROCHE AG 发明人 HILPERT HANS
分类号 C07D413/12;A61K31/536;A61P25/00;C07D265/12 主分类号 C07D413/12
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