发明名称 |
Glucagon-like insulinotropic peptides, compositions and methods |
摘要 |
The present invention provides novel complexes consisting of certain GLP-1 molecules associated with a divalent metal cation that is capable of co-precipitating with a GLP-1 molecule. Pharmaceutical compositions and methods of using such complexes for enhancing the expression of insulin in B-type islet cells is claimed, as is a method for treating maturity onset diabetes mellitus in mammals, particularly humans.
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申请公布号 |
US6410513(B1) |
申请公布日期 |
2002.06.25 |
申请号 |
US20000573809 |
申请日期 |
2000.05.18 |
申请人 |
ELI LILLY AND COMPANY |
发明人 |
GALLOWAY JOHN A.;HOFFMAN JAMES A. |
分类号 |
A61K38/26;A61K38/00;A61K38/28;A61K47/02;A61K47/48;A61P3/08;A61P3/10;A61P43/00;C07K14/575;C07K14/605;C07K14/62;(IPC1-7):A61K38/00 |
主分类号 |
A61K38/26 |
代理机构 |
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代理人 |
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地址 |
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