| 主权项 |
1. A compound or its tautomeric, enantiomeric or diastereomeric form or a pharmaceutically acceptable salt, said compound having the formula: wherein: A, B, D, E, G and J are independently selected from the group consisting of N or C substituted with one of R2, R3, R4, R5, R6 or R7, wherein if A, B, D, E, G, or J are N, then R2, R3, R4, R5, R6 or R7 represent a free electron pair at the N atom; R1 is selected from the group consisting of hydrogen and methyl; R2, R3, R4, R5, R6 and R7 are independently of one another, when attached to N, a free electron pair, or, when attached to C, are selected from the group consisting of hydrogen, halogen, methyl, methoxy, hydroxyl, —NH2, and —SO2CH3; R8 is selected from the group consisting of hydrogen and (C1-C6)-alkyl; and Y is selected from the group consisting of substituted or unsubstituted C6 aryl, and substituted or unsubstituted heteroaryl comprising 6 member atoms and having at least one of N, N═O, NH, or N-(C1-C6)-alkyl as ring members, wherein when Y is substituted aryl or substituted heteroaryl, substituents are selected from the group consisting of halogen, (C1-C6)-alkyl, (C1-C6)-alkoxy, hydroxyl, —OBn, —COOMe, —COOH, —NH2, —CH2OH, N-di-(C1-C6)-alkyl, and —N—SO2CH3, with the proviso that where A, B, D, E, G and J are each carbon, and R1, R2, R3, R4, R5, R6, R7 and R8 are each hydrogen, if X is and Y is C6-aryl, then Y is substituted, and if X is and Y is a substituted C6-aryl, then a substituent may not be —NH2. |
