| 摘要 |
PROBLEM TO BE SOLVED: To obtain a prophylactic and therapeutic agent with high safety having improving effects on cardiac failure in various cardiac performances, useful as a prophylactic and therapeutic agent based on a completely new action mechanism. SOLUTION: This prophylactic and therapeutic agent for cardiac failure comprises a compound represented by general formula (1) [R1 and R2 are each independently a hydrogen atom or a lower alkyl group; R3 to R6 are each independently a lower alkyl group, a lower alkoxy group, a halogen atom, an amino group, a cyano group. a nitro group or a hydroxy group; R7 and R8 are each independently a hydrogen atom or a lower alkyl group; X and Y are each independently an oxygen atom, a sulfur atom or an amino group], its salt, solvate or a solvate of the salt.
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