| 摘要 |
PROBLEM TO BE SOLVED: To provide a workability-improved, industrially useful and efficient method for producing an acetophenone compound containing trifluoromethyl group. SOLUTION: This method for producing an acetophenone compound containing trifluoromethyl group such as 3,5-bis(trifluoromethyl)acetophenone comprises reacting a halogenobenzene containing trifluoromethyl group such as 3,5-bis(trifluoromethyl)bromobenzene with an alkylmagnesium halide such as ethylmagnesium bromide and reacting the thus obtained phenylmagnesium halide containing trifluoromethyl group such as 3,5-bis(trifluoromethyl) phenylmagnesium bromide with acetic anhydride.
|
