发明名称 Combinations of ileal bile acid transport inhibitors and fibric acid derivatives for cardiovascular indications.
摘要 The present invention provides combinations of cardiovascular therapeutic compounds for the prophylaxis or treatment of cardiovascular disease including hypercholesterolemia and atherosclerosis. Combinations disclosed include an ileal bile acid transport inhibitor combined with a cholesteryl ester transport protein (CETP) inhibitor, a fibric acid derivative, a nicotinic acid derivative, a microsomal triglyceride transfer protein inhibitor, a cholesterol absorption antagonist, a phytosterol, a stanol, an antihypertensive agent, or others. Further combinations include a CETP inhibitor with a fibric acid derivative, a nicotinic acid derivative, a bile acid sequestrant, a microsomal triglyceride transfer protein inhibitor, a cholesterol absorption antagonist, or others.
申请公布号 ZA200105061(B) 申请公布日期 2002.06.20
申请号 ZA20010005061 申请日期 2001.06.20
申请人 G. D. SEARLE LLC. 发明人 BRADLEY T KELLER;KEVIN C GLENN;JOSEPH R. SCHUH
分类号 A61K45/06;A61K;A61K31/095;A61K31/365;A61K31/397;A61K31/4178;A61K31/55;A61K31/554;A61K31/575;A61K31/585;A61K31/77;A61K45/00;A61P;A61P3/06;A61P9/00;A61P9/10;C07D 主分类号 A61K45/06
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