发明名称 |
A LIGAND FOR ENHANCING ORAL AND CNS DELIVERY OF BIOLOGICAL AGENTS |
摘要 |
Provided herein is a novel and useful Ligand comprising a peptide comprising an amino acid sequence of SEQ. ID. NO.:6, an analog, a derivative, or a variant thereof, which increases the absorption of biological agents across the blood brain barrier and the gastrointestinal barrier. As a result, a Ligand of the present invention increases the bioavailability of biological agents administered orally. |
申请公布号 |
WO0190139(A3) |
申请公布日期 |
2002.06.20 |
申请号 |
WO2001IB00926 |
申请日期 |
2001.05.07 |
申请人 |
SUPRATEK PHARMA INC. |
发明人 |
TCHISTIAKOVA, LIOUDMILA;LI, SHENGMIN;PIETRZYNSKI, GRZEGORZ;ALAKHOV, VALERY |
分类号 |
C12N15/09;A61K38/00;A61K45/00;A61K48/00;A61P25/00;C07K7/00;C07K7/06;C07K7/08;C07K14/505;C12N1/15;C12N1/19;C12N1/21;C12N5/10 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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