发明名称 A LIGAND FOR ENHANCING ORAL AND CNS DELIVERY OF BIOLOGICAL AGENTS
摘要 Provided herein is a novel and useful Ligand comprising a peptide comprising an amino acid sequence of SEQ. ID. NO.:6, an analog, a derivative, or a variant thereof, which increases the absorption of biological agents across the blood brain barrier and the gastrointestinal barrier. As a result, a Ligand of the present invention increases the bioavailability of biological agents administered orally.
申请公布号 WO0190139(A3) 申请公布日期 2002.06.20
申请号 WO2001IB00926 申请日期 2001.05.07
申请人 SUPRATEK PHARMA INC. 发明人 TCHISTIAKOVA, LIOUDMILA;LI, SHENGMIN;PIETRZYNSKI, GRZEGORZ;ALAKHOV, VALERY
分类号 C12N15/09;A61K38/00;A61K45/00;A61K48/00;A61P25/00;C07K7/00;C07K7/06;C07K7/08;C07K14/505;C12N1/15;C12N1/19;C12N1/21;C12N5/10 主分类号 C12N15/09
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