发明名称 |
Nucleic acid arrays and methods of synthesis |
摘要 |
The present invention generally relates to high density nucleic acid arrays and methods of synthesizing nucleic acid sequences on a solid surface. Specifically, the present invention contemplates the use of stabilized nucleic acid primer sequences immobilized on solid surfaces, and circular nucleic acid sequence templates combined with the use of isothermal rolling circle amplification to thereby increase nucleic acid sequence concentrations in a sample or on an array of nucleic acid sequences.
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申请公布号 |
US2002076716(A1) |
申请公布日期 |
2002.06.20 |
申请号 |
US20010886779 |
申请日期 |
2001.06.21 |
申请人 |
TRUSTEES OF BOSTON UNIVERSITY |
发明人 |
SABANAYAGAM CHANDRAN R.;SANO TAKESHI;MISASI JOHN;HATCH ANSON;CANTOR CHARLES |
分类号 |
C07B61/00;C07H21/00;C12P19/34;C12Q1/68;C40B40/06;(IPC1-7):C12Q1/68;C12M1/34 |
主分类号 |
C07B61/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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