发明名称 PHENYLACETAMIDO- PYRAZOLE DERIVATIVES AND THEIR USE AS ANTITUMOR AGENTS
摘要 Phenylacetamido-pyrazoles of Formula (I) and, more particularly, N-(5- cycloalkyl-1H-pyrazol-3-yl) phenylacetamido derivatives, optionally further substituted as reported in the description; or pharmaceutically acceptable salts thereof; are useful in the treatment of cell proliferative disorders, e.g.cancer, associated with an altered cell cycle dependent kinase activity. Formula (I).
申请公布号 CA2430151(A1) 申请公布日期 2002.06.20
申请号 CA20012430151 申请日期 2001.11.22
申请人 PHARMACIA ITALIA S.P.A. 发明人 TRAQUANDI, GABRIELLA;BRASCA, MARIA GABRIELLA;PEVARELLO, PAOLO;ORSINI, PAOLO;VILLA, MANUELA;AMICI, RAFFAELLA;PIUTTI, CLAUDIA;LONGO, ANTONIO;VARASI, MARIO
分类号 A61K31/4155;A61K31/422;A61P9/10;A61P13/08;A61P19/02;A61P25/00;A61P25/28;A61P31/12;A61P35/00;A61P37/06;A61P43/00;C07D231/40;C07D401/12;C07D403/12;C07D413/12;(IPC1-7):C07D231/40;A61K31/415 主分类号 A61K31/4155
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