Substituted spiro-piperidine derivatives of structural formula (I) are tachykinin receptor antagonists of use, for example, in the treatment or prevention of pain, inflammation, migraine, emesis and postherpetic neuralgia.
申请公布号
YU59098(A)
申请公布日期
2002.06.19
申请号
YU19980000590
申请日期
1997.06.17
申请人
MERCK SHARP & DOHME LIMITED
发明人
BAKER, RAYMOND;CURTIS, NEIL ROY;ELLIOT, JASON MATTHEW;HARRISON, TIMOTHY;HOLLINGWORTH, GREGORY JOHN;JACKSON, PHILIP STEPHEN;KULAGOWSKI, JANUSZ JOZEF;SEWARD, EILEEN MARY;SWAIN, CHRISTOPHER JOHN;WILLIAMS, BRIAN JOHN