发明名称 IMPROVED METHOD FOR PRODUCING THIAZOLIDINEDIONES, AND NEW THIAZOLIDINEDIONES
摘要 The invention relates to an improved method for producing compounds of the formula (III) wherein A represents CH=CH or S, W represents O, X represents S, O or NR2, the radical R2 being hydrogen or C1-C6alkyl, Y represents CH or N, R represents naphthyl, thienyl or phenyl which is optionally mono- or disubstituted with C1-C3 alkyl, CF3, C1-C3 alkoxy, F, CI or bromine, R1 represents hydrogen or C1-C6 alkyl and n represents 1-3 by reacting compounds of the formula (IV) wherein A, W, X, Y, R, R1 and n have the meaning given above with activated aluminum in a protic solvent. The invention also relates to new compounds of the formula III and medicaments containing these compounds.
申请公布号 YU46699(A) 申请公布日期 2002.06.19
申请号 YU19990000466 申请日期 1998.03.17
申请人 ROCHE DIAGNOSTICS GMBH. 发明人 WOLFF, HANS-PETER;WITTE, ERNST-CHRISTIAN;KUHNLE, HANS-FRIEDER
分类号 A61K31/427;A61P3/10;C07D263/00;C07D277/00;C07D333/00;C07D417/12;C07D417/14 主分类号 A61K31/427
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