| 摘要 |
A cancerous metastasis inhibitor containing a benzoic acid derivative which is represented by general formula (I) and has a remarkably excellent cancerous metastasis inhibitory effect as the active ingredient; the use of the benzoi c acid derivatives for producing the cancerous metastasis inhibitor; and a method of inhibiting cancerous metastasis by administering an effective amou nt of the benzoic acid derivative to mammals. In said formula (I), R1, R2, R3 a nd R4 may be the same or different and each represents hydrogen, hydroxy or trimethylsilyl, or alternatively R3 and R4 are bonded to each other to represent lower alkyl-substituted tetramethylene; and X represents -COCH=C(O H)- , -NHCO- or -CONH-, provided when R3 and R4 are bonded to each other to represent lower alkyl-substituted tetramethylene, X represents -COCH=C(OH)- or -CONH-.
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