发明名称 |
Cell arrays and the uses thereof |
摘要 |
The present invention provides cell arrays comprising a plurality of tubes containing populations of cells that are immobilized therein. The arrays are particularly useful for conducting comparative cell-based analyses. Specifically, the subject arrays allow protein-protein interactions to be studied in multiple types of cell simultaneously. The arrays also support simultaneous detection of the differential expression of a target polynucleotide in a multiplicity of cell types derived from multiple subjects. The subject arrays further permit high throughput screening for candidate modulators of a signal transduction pathway of interest. Further provided by the invention are kits, computer-implemented methods and systems for conducting the comparative cell-based analyses.
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申请公布号 |
US6406840(B1) |
申请公布日期 |
2002.06.18 |
申请号 |
US19990466011 |
申请日期 |
1999.12.17 |
申请人 |
BIOMOSAIC SYSTEMS, INC. |
发明人 |
LI RONGHAO;MATHER JENNIE P. |
分类号 |
G01N33/48;B01J19/00;C12M1/00;C12N5/02;C12N11/04;C12N11/08;C12N11/12;C12N15/09;C12Q1/68;C40B30/04;C40B60/14;G01N1/36;G01N33/53;G01N33/566;G01N33/58;G01N33/68;G01N37/00;(IPC1-7):C12N5/02;C12N1/04 |
主分类号 |
G01N33/48 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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