| 摘要 |
A substance for use in the treatment of cancer, includes a compound selected from metallocenyl beta-diketones Mc-CO-CZ1Z2-CO-R. Mc is Fc (ferrocenyl), Rc (ruthenocenyl) or Oc (osmocenyl), R is 11, alkyl or aryl and Z1 and Z2 are H, alkyl, aryl or substituted alkyl, ferrocenyl, the enol forms of the beta-diketones and metal complexes of the beta-diketones of the general formula M(beta-diketonato)A<1>, M(beta-diketonato)A<1>A<2>, M(beta-diketonato)A<1>B<1>B<2>, M(beta-diketonato)B<1>B<2 >and M(beta-diketonato)B<1>B<2>B<3>B<4>. M is Rh or Ir, A<1 >and A<2 >are cyclic dienes having 6-8 carbons, or linear alkenes having 2-7 carbons. B<1>, B<2>, B<3 >and B<4 >are selected from CO, P(R<1>R<2>R<3>), P(OR<1>)(OR<2>)(OR<3>), R<4 >and X in which R<1>, R<2>, R<3 >and R<4 >are independently alkyl, phenyl or ferrocenyl, and X is a halide or a pseudohalide. |
