5-arüül-3-(8-asabitsüklo[3.2.1]okt-3-üül)-1,3,4-oksadiasool-2(3H)-ooni derivaadid kui 5-HT4 retseptori ligandid

摘要

Compound of general formula (I)in which R1 represents an alkyl or cycloalkylmethyl group, X1 represents a hydrogen or halogen atom or an alkoxy group, or alternatively OR1 and X1 together represent an -OCH2O-, -O(CH2)2-, -O(CH2)3-, -O(CH2)2O- or -(CH2)3O- group, X2 represents a hydrogen atom or an amino group, X3 represents a hydrogen or halogen atom, and R2 represents a hydrogen atom, an optionally substituted alkyl group, an optionally substituted phenylalkyl group or a group -(CH2)nCO-Z in which n represents a number from 1 to 6 and Z represents a 1-piperidyl group. Therapeutic application.