发明名称 |
METHODS AND COMPOSITIONS FOR THE DIAGNOSIS AND TREATMENT OF VIRAL DISEASE USING 55092 |
摘要 |
The present invention relates to methods and compositions for the diagnosis and treatment of viral disease, including, but not limited to, herpes simplex virus, hepatitis B and hepatitis C viral infection. Specifically, the present invention identifies PLD 55092 genes which are differentially expressed in virus infected cells, relative to their expression in normal, uninfected cells. The present invention describes methods for the diagnostic evaluation and prognosis of various viral diseases, and for the identification of subjects exhibiting a predisposition to such conditions. The present invention provides methods for the diagnostic monitoring of patients undergoing clinical evaluation for the treatment of viral disease, and for monitoring the efficacy of compounds in clinical trials. The present invention also provides methods for the identification and therapeutic use of compounds as treatments of viral disease. |
申请公布号 |
WO0245570(A2) |
申请公布日期 |
2002.06.13 |
申请号 |
WO2001US46358 |
申请日期 |
2001.12.06 |
申请人 |
MILLENNIUM PHARMACEUTICALS, INC.;COOK, JAMES, W.;MEYERS, RACHEL |
发明人 |
COOK, JAMES, W.;MEYERS, RACHEL |
分类号 |
A61P31/00;C12Q1/68;C12Q1/70;G01N33/569;G01N33/576 |
主分类号 |
A61P31/00 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|