发明名称 LABORATORY SCALE MILLING PROCESS
摘要 There is provided a process fo reducing particle size of a drug, the process comprising: (a) a step of dispersing about 10 g or less of the drug in a suitable volume of a liquid dispersion medium to form a suspension; (b) a st ep of bringing together in a vessel grinding media, magnetically activatable means for stirring and the suspension; (c) a step of magnetically activating the means for stirring to effect milling of the suspension to a weight avera ge particle size not greater than about 1 .mu.m; and (d) a step of separating t he resulting milled suspension from the grinding media and the magnetically activatable means for stirring.
申请公布号 CA2436574(A1) 申请公布日期 2002.06.13
申请号 CA20012436574 申请日期 2001.12.05
申请人 PHARMACIA CORPORATION 发明人 HASKELL, ROYAL J.
分类号 A61J3/02;A61K9/08;A61K9/10;A61K9/14;A61K9/16;A61K9/48;A61K47/04;A61K47/20;A61K47/32;A61K47/34;A61K47/38;A61K47/44;A63G31/16;B02C17/00;B02C17/16;B02C17/20;G09B5/14;G09B9/08;(IPC1-7):A61K9/14 主分类号 A61J3/02
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