| 摘要 |
<p>The present invention relates to a controlled release system of biologically active ingredients or sensory markers to the oral cavity and mucous membranes of various tissues. Preferably, the controlled release system comprises a biologically active agent or sensory marker incorporated into substantially solid nano-particles encapsulated in moisture sensitive micro-particles. The nano-particles have a hydrophobic core and a positively charged surface. The positively charged surface is formed by a cationic surfactant that is entrapped and fixed to the particle's surface as showed in Fig. 1.</p> |
