发明名称 |
OPTICAL DETERMINATION OF GLUCOSE UTILIZING BORONIC ACID ADDUCTS |
摘要 |
The present invention concerns an improved optical method and optical sensing device for determining the levels of polyhydroxyl-substituted organic molecules in vitro and/or in vivo in aqueous media. In particular, a sensory devise is implemented in a mammal to determine sugar levels. Specifically, a dye is combined with a conjugated nitrogen-containing heterocyclic aromatic boronic acid-substituted bis-onium compound in the presence of a sugar, such as fructose or glucose. The viologens are preferred as the aromatic conjugated nitrogen-containing boronic acid substituted compounds. The method is useful to determine sugar levels in a human being.
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申请公布号 |
CA2436590(A1) |
申请公布日期 |
2002.06.13 |
申请号 |
CA20012436590 |
申请日期 |
2001.12.05 |
申请人 |
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA |
发明人 |
SINGARAM, BAKTHAN;WESSLING, RITCHIE A. |
分类号 |
G01N21/64;G01N33/52;G01N33/543;(IPC1-7):C07D401/14;A61K49/00;C07D401/10;G01N33/66 |
主分类号 |
G01N21/64 |
代理机构 |
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主权项 |
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地址 |
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