摘要 |
A compound of formula (I) and pharmaceutically acceptable salts, solvates an d hydrolysable esters thereof wherein: X1 is O or S; X2 is O or S; n is 1-3; O ne of Y and Z is N, and the other is O; R1 and R2 are independently halogen, H, CH3, OCH3 or C1-3 alkyl; Each R3 independently is halogen, CF3, C1-6 straigh t or branched alkyl; R4 and R5 are independently H or C1-3 alkyl. y is 0, 1, 2 , 3, 4 or 5.
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