SUBSTRATE FOR TISSUE REGENERATION, MATERIAL FOR TRANSPLANTATION, AND PROCESSES FOR PRODUCING THESE

摘要

A 1% aqueous hyaluronic acid solution containing a water-soluble epoxy compound as a crosslinking agent is heated and concentrated to obtain an intermolecularly crosslinked hyaluronic acid. Subsequently, this crosslinked compound is freeze-dried under vacuum to obtain a hyaluronic acid sponge. The sponge is impregnated with an atherocollagen solution and then freeze-dried under vacuum. Thus, a substrate for tissue regeneration is obtained.