ASYMMETRIC LIGANDS USEFUL FOR TRANSITION METAL CATALYZED BOND FORMING REACTIONS AND EPOXIDE REACTIONS THEREWITH

摘要

A novel ligand having the Formula 1 structure has proved remarkably successful in the amination of butadiene monoepoxide, which is a potentially desirable substrate for an asymmetric synthesis providing access to each enantiomer of vinylglycinol. This and other ligands described are useful for chiral induction of bond forming reactions with an epoxide substrate.