发明名称 |
Process and system for uniform release drug delivery |
摘要 |
<p>A controlled-release dosage form for a phamaceutically-active agent comprises a core, in which the agent is dispersed, surrounded by a diffusion-limiting sleeve. The agent is released at a zero-order or approximately linear rate because the release rate of the agent will be governed entirely by erosion from exposed core surfaces; the surface area of which does not change substantially during the release process. Such a product may be made by coextruding the core and sleeve material and slicing the extrudate. <IMAGE></p> |
申请公布号 |
EP1213014(A2) |
申请公布日期 |
2002.06.12 |
申请号 |
EP20010128075 |
申请日期 |
2001.11.27 |
申请人 |
WARNER-LAMBERT COMPANY |
发明人 |
FESSEHAIE, MEBRAHTU;GHEBRE-SELLASSIE, ISAAC;MOLLAN, MATTHEW JOSEPH JR.;MAYASSI, MONZER MICHAEL;WOLDEGABER, HAIMANOT;DYAR, STEPHEN CRAIG |
分类号 |
A61K9/00;A61K9/20;A61K9/22;A61K31/427;A61K47/14;A61K47/32;A61K47/34;A61K47/38;A61P3/10;(IPC1-7):A61K9/22 |
主分类号 |
A61K9/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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