发明名称 |
Genetically engineered herpes virus for the treatment of cardiovascular disease |
摘要 |
The present invention provides methods of expressing a nucleic acid or producing a proteinaceous composition encoded by a nucleic acid in vascular and cardiovascular cells by administration of a herpesvirus vector. The present invention provides methods of producing a therapeutic benefit in vascular and cardiovascular tissue by administration of a herpesvirus vector. In additional aspects, the invention concerns combination therapies for vascular and cardiovascular diseases comprising administration of a herpesvirus vector and treatment with at least one addition pharmacological agent or surgical procedure. |
申请公布号 |
AU1788502(A) |
申请公布日期 |
2002.06.11 |
申请号 |
AU20020017885 |
申请日期 |
2001.11.28 |
申请人 |
THE UNIVERSITY OF CHICAGO |
发明人 |
LEWIS B. SCHWARTZ;RALPH R WEICHSELBAUM;BERNARD ROIZMAN |
分类号 |
C12N15/09;A61K31/7088;A61K35/76;A61K38/00;A61K45/00;A61K48/00;A61P7/02;A61P9/00;A61P9/04;A61P9/06;A61P9/10;A61P9/12;A61P37/02;A61P43/00;C12N7/04;C12N15/869 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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