发明名称 METHOD FOR PRODUCING AN IMMUNOTROPIC ANTIVIRAL PREPARATION
摘要 The invention relates to the chemical pharmaceutical industry, in particular to a method for producing an immunotropic preparation exhibiting a high antiviral activity with respect to RNA and DNA viruses. In order to produce the inventive preparation, fat-free sturgeon or salmon milt, or a calf thymus, or chicken blood, or porcine liver is pulverised and homogenised in a saline citrate solution. The produced homogenate is incubated in the presence of a detergent, a calcium chlorine solution being added at a high temperature. Afterwards, said homogenate is treated by ultrasound, a sorbent and detergent and concentrated, thereby producing a white amorphous deposit of DNA which has the following characteristics: a molecular mass ranging from 270 to 500 kD, a hyperchromatic action not less than 37 %, a protein content of less than 1 %. The DNA deposit is dried and the obtained powder is diluted in an aqueous solution of the following transition metal: Zn, Co, Mn, Sb, whereby a 1.5 % sterilised solution having a hyperchromatic action equal to or higher than 10 % is obtained.
申请公布号 WO0243740(A1) 申请公布日期 2002.06.06
申请号 WO2001RU00171 申请日期 2001.04.24
申请人 KAPLINA, ELLI NIKOLAEVNA;LADYGINA, ALEXANDRA YUREVNA;KAPLIN, VALERY YUREVICH;VAINBERG, MIHAIL YUREVICH 发明人 KAPLINA, ELLI NIKOLAEVNA;LADYGINA, ALEXANDRA YUREVNA;KAPLIN, VALERY YUREVICH;VAINBERG, MIHAIL YUREVICH
分类号 A61K31/70;A61K31/711;A61K33/24;A61K33/30;A61K33/32;A61K35/14;A61K35/26;A61K35/407;A61K35/60;A61P31/14;(IPC1-7):A61K31/70;C07H21/04;A61K35/28;A61K35/55 主分类号 A61K31/70
代理机构 代理人
主权项
地址