The invention relates to the identification of C1 bacteriophage genes that express protein involved in the lysis of bacterial cells during the phage life cycle, lysin and holin. The invention further relates to methods for lysing certain bacteria using lysin, which are useful for example in the treatment of an oral cavity bacterial infection.
申请公布号
WO0190331(A3)
申请公布日期
2002.06.06
申请号
WO2001US16824
申请日期
2001.05.23
申请人
THE ROCKEFELLER UNIVERSITY;NELSON, DANIEL, C.;FISCHETTI, VINCENT, A.