摘要 |
A method, system, and computer program product is provided for analyzing of a microcirculatory system to determine the quantity of various blood components, such as red blood cells. The images are analyzed to identify vessel structure, and determine the variance in measurable parameters, such as the vessel diameter or optical density. In an embodiment of the present invention, the coefficient of variation is determined for the diameter measurements along the vessel and a fractional volume value is calculated for the red blood cells. The fractional volume value is used to estimate the hematocrit (Hct). In another embodiment, the coefficient of variation is determined from a plurality of optical density measurements made at multiple points along the vessel, and the fractional volume value and Hct are calculated from the coefficient of variation of the optical density measurements. In yet another embodiment, the variation in optical density is measured at a single point for a time series of images of a vessel, and a fractional volume and hematocrit are calculated from the coefficient of variation.
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