| 摘要 |
The invention provides an improved method for potentiating the antineoplasti c activity of 5-fluorouracil with levamisole, or with an analogue thereof. Specifically, the invention provides regimens wherein levamisole is administered contemporaneously with the administration of 5-fluorouracil, thereby increasing the exposure of tumor tissue to the simultaneous presence of the two drugs. The invention further provides methods for the parenteral administration of levamisole, thereby overcoming the disadvantages associate d with inter-patient variability in the bioavailability of oral.
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