PHOTOCHEMICAL INTERNALIZATION FOR VIRUS-MEDIATED MPHOTOCHEMICAL INTERNALIZATION FOR VIRUS-MEDIATED MOLECULE DELIVERY INTO THE CYOSOL OLECULE DELIVERY INTO THE CYOSOL

摘要

The present invention provides a method for introducing a molecule into the cytosol of a cell in which the cell is contacted with a photosensitising agent, the cell is irradiated with light of a wavelength effective to activa te the photosensitising agent and, substantially at the same time or after the irradiation, the cell is contacted with the molecule to be introduced, particularly for use in cancer treatment, gene therapy and vaccination.