发明名称 |
RECOMBINATION M. TUBERCULOSIS MYCOBACTERIUM AUXOTROPHIC FOR LEUCINE AND VACCINES USING SAME |
摘要 |
The present invention provides a recombinant M. tuberculosis mycobacterium that is auxotrophic for leucine. The present invention also provides a vaccine comprising a recombinant M. tuberculosis mycobacterium that is auxotrophic for leucine, as well as a method for treating or preventing tuberculosis in a subject comprising administering to the subject a recombinant M. tuberculosis mycobacterium that is auxotrophic for leucine in an amount effective to treat or prevent tuberculosis in the subject.
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申请公布号 |
US2002068067(A1) |
申请公布日期 |
2002.06.06 |
申请号 |
US19990349739 |
申请日期 |
1999.07.08 |
申请人 |
HONDALUS MARY K.;BLOOM BARRY R.;JACOBS WILLIAM R. |
发明人 |
HONDALUS MARY K.;BLOOM BARRY R.;JACOBS WILLIAM R. |
分类号 |
C12N15/52;(IPC1-7):A61K39/02 |
主分类号 |
C12N15/52 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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