Pharmaceutical carrier preparation applicable to mucosal surfaces

摘要

The present invention relates to a non water-soluble pharmaceutical carrier which adheres to mucosal surfaces and body tissues upon application and forms a film, providing protection and delivery of pharmaceutical to the site of the application, surrounding body tissues, and bodily fluids. The gel comprises a volatile or diffusing nonaqueous solvent and at least one non water-soluble alkyl cellulose or hydroxyalkyl cellulose. A bioadhesive polymer may also be added. The gel provides an effective residence time with ease of use. The residence time may be adjusted by adding a component which acts to adjust the kinetics or erodability of the carrier.