ADSORBENT FOR TUMOR NECROSIS FACTOR ALPHA, METHOD OF REMOVAL BY ADSORPTION, AND ADSORPTION DEVICE USING SAID ADSORBENT

摘要

The present invention relates to an adsorbent being capable of efficiently removing tumor necrosis factor- alpha (TNF- alpha ) in a body fluid, an adsorber using the adsorbent and a process for adsorbing and removing TNF- alpha , namely an adsorbent of TNF- alpha , wherein onto a water-insoluble carrier a compound having a functional group represented by the formula (I): wherein X is an anionic functional group, A is a substituent group except for the anionic functional group, n is an integer of 0 to 4 and in case n is at least 2, groups A, the number of which is n, may be the same or different from each other; a process for adsorbing and removing TNF- alpha , which comprises coming the adsorbent into contact with a body fluid; and an adsorber for adsorbing TNF- alpha wherein a vessel having an inlet and an outlet for a body fluid and being equipped with a means for preventing the adsorbent from flowing to the outside of the vessel, is charged with the adsorbent.