发明名称 Glucose-containing preparation
摘要 A neutral glucose-containing preparation with excellent stability and a near physiological pH, as a transfusion preparation with minimal glucose degradation by-products and a greatly reduced formic acid content; specifically, a glucose-containing preparation comprising separately housed first and second solutions, the first and second solutions satisfying the following conditions:(a) the first solution contains 2-50% glucose, and its pH is adjusted to 3-5 with an organic acid buffer solution;(b) the second solution contains an alkalizing agent, and has a pH value of 8-13 as a pH adjustor for the first solution; and(c) the glucose concentration is 1-15% in the preparation solution obtained by mixing the first solution and second solution, and the pH of the solution is in a range of 6-8.It is used particularly as a peritoneal perfusate, such as a perfusate for Continuous Ambulatory Peritoneal Dialysis (CAPD).
申请公布号 US6399110(B1) 申请公布日期 2002.06.04
申请号 US20000485300 申请日期 2000.04.27
申请人 SHIMIZU PHARMACEUTICAL CO., LTD. 发明人 KIKUCHI TAKUMI;HIRANO KOUICHI
分类号 A61K45/06;A61M1/28;(IPC1-7):A01N59/00;A61B19/00;B65D25/08 主分类号 A61K45/06
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