发明名称 |
Phosphoglycolipid and methods for its use |
摘要 |
The invention concerns a novel phosphoglycolipid compound. The compound of the subject invention is 2-Deoxy-6-O-[2-deoxy-4-O-phosphono-3-O-[(R)-3-tetradecanoyloxytetradecanoyl]-2-[(R)-3-octadecanoyloxytetradecanoylamino]-beta-<SMALLCAPS>D</SMALLCAPS>-glucopyranosyl]-2-[(R)-3-hexadecanoyloxytetradecanoylamino]-<SMALLCAPS>D</SMALLCAPS>-glucopyranose and pharmaceutically acceptable salts thereof. The compound is not immunoreactive, not pyrogenic, not toxic but is active in ameliorating tissue damage due to ischemia/reperfusion injury. Methods for using the subject compound to protect against reversible and irreversible damage due to ischemia/reperfusion injury are also disclosed.
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申请公布号 |
US6399590(B2) |
申请公布日期 |
2002.06.04 |
申请号 |
US20010927246 |
申请日期 |
2001.08.10 |
申请人 |
CORIXA CORPORATION |
发明人 |
ELLIOTT GARY T.;WEBER PATRICIA A.;SOWELL C. GREGORY |
分类号 |
C07H13/04;A61K31/661;A61K31/739;A61K47/10;A61K47/34;A61P1/00;A61P9/00;A61P9/10;A61P17/02;C07H5/04;C07H11/04;C07H13/06;(IPC1-7):A61K31/715;C08B37/00 |
主分类号 |
C07H13/04 |
代理机构 |
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