发明名称 |
Method of isolating receptor and ligand DNA |
摘要 |
Disclosed herein are compositions and methods which are useful in the identification and isolation of components involved in transmembrane receptor-mediated signaling. Such components include the receptors themselves (e.g., tyrosine kinase receptors, cytokine receptors and tyrosine phosphatase receptors), as well as ligands which bind the receptors and modulators of the downstream intracellular catalytic event which characterizes receptor-mediated signalling. Two novel ligands for the FGF receptor and the nucleotide sequences encoding them are also described.
|
申请公布号 |
US6399386(B1) |
申请公布日期 |
2002.06.04 |
申请号 |
US20000507773 |
申请日期 |
2000.02.18 |
申请人 |
PRESIDENT AND FELLOWS OF HARVARD COLLEGE |
发明人 |
KIRSCHNER MARC W.;KINOSHITA NORIYUKI |
分类号 |
A61K38/00;C07K14/46;C07K14/705;C07K16/18;C12N15/10;C12N15/81;(IPC1-7):C12N15/74 |
主分类号 |
A61K38/00 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|